| Preliminary Round | Date: | 16th January 2022 |
| Blackbrook Royals ARLFC | V | Westhoughton Lions U16s |
| East Hull | V | Siddal |
| West Hull ARLFC | V | Wath Brow Hornets |
| Leigh East ARLFC | V | Waterhead |
| Cutsyke Raiders | V | Salford City Roosters |
| Crosfields ARLFC U15s | V | Rochdale Mayfield Blacks |
| Leigh Miners Rangers | V | Limehurst Lions |
| Skirlaugh ARLFC | V | Rylands Sharks ARLFC |
| Folly Lane ARLFC | V | Culcheth Eagles |
| Latchford Giants | V | Golborne Parkside |
| Halton Farnworth Hornets Reds | V | Hull Wyke ARLFC |
| Ulverston ARLFC | V | Rochdale Mayfield Blues |
| Drighlington ARLFC | V | West Bank Bears Under 15s |
| Saddleworth Rangers U15s | V | Hunslet Club Parkside |
| Greetland Allrounders | V | Hindley ARLFC |
| Crosfields ARLFC | V | Saddleworth Rangers U16s |
| East Leeds ARLFC | V | Thornhill Trojans |
| Lock Lane | V | Hensingham ARLFC |
| Elland RLFC | V | Normanton Knights |
| Salford City Roosters Under 15s | V | Featherstone Lions |
| Birkenshaw Bluedogs | V | Shaw Cross Sharks |
| Moldgreen ARLFC | V | Wigan St Patricks |
| Guiseley Rangers | V | Thatto Heath Crusaders |
| Wigan St Judes U15s | V | Oulton Raiders |
| BYES | ||
| Dalton ARLFC | ||
| Illingworth ARLFC | ||
| Lowca ARLFC | ||
| Rochdale Mayfield Whites | ||
| Stanningley | ||
| Wigan St Cuthberts | ||
| Wigan St Judes U16s | ||
| York Acorn |
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